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Browsing CSF Metabolite Diseases and Conditions
Clicking on any metabolite link will take you to the Human Metabolome Database.
Alzheimer's disease (104300 )
| Metabolite | Concentration in CSF | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 1-Methylhistidine (HMDB0000001) | 2.6 +/- 1.13 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Folic acid (HMDB0000121) | 0.0056 +/- 0.005 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Methylhistidine (HMDB0000479) | 2.48 +/- 1.58 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Homocysteine (HMDB0000742) | 14.2 +/- 1.7 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Acetylcholine (HMDB0000895) | 0.01 +/- 0.005 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Fumaric acid (HMDB0000134) | 11.0 (2.00-20.0) uM | Abnormal | Elderly (>65 years old) | Both | details | |
| D-Glucose (HMDB0000122) | 3700.0 (3200.0-4200.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Glutamine (HMDB0000641) | 254.0 (152.0-356.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Glycerophosphocholine (HMDB0000086) | 6.9 +/- 3.2 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Succinic acid (HMDB0000254) | 55.0 (19.0-91.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| 24-Hydroxycholesterol (HMDB0001419) | 0.0061 (0.0058-0.0064) uM | Abnormal | Elderly (>65 years old) | Both | details | |
| 27-Hydroxycholesterol (HMDB0002103) | 0.0038 +/- 0.0003 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Dopamine (HMDB0000073) | 0.000078 (0.0000065-0.00015) uM | Abnormal | Adult (>18 years old) | Both | details | |
| 3,4-Dihydroxybenzeneacetic acid (HMDB0001336) | 0.0023 (0.00051-0.0042) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 4-Hydroxynonenal (HMDB0004362) | 0.40 +/- 0.030 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 8-Hydroxyguanine (HMDB0002032) | 0.19 (0.15-0.23) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Pentosidine (HMDB0003933) | 12.5 (12.0-13.0) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 4-Hydroxynonenal (HMDB0004362) | 0.36 +/- 0.03 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Homocysteine (HMDB0000742) | 0.12 +/- 0.062 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Fe2+ (HMDB0000692) | 2.5 +/- 1.8 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Manganese (HMDB0001333) | 14.6 +/- 13.7 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Mannitol (HMDB0000765) | 5.54 +/- 0.82 uM | Abnormal | Not Specified | Not Specified | details | |
| Methylmalonic acid (HMDB0000202) | 0.30 +/- 0.12 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| myo-Inositol (HMDB0000211) | 158.8 +/- 27.2 uM | Abnormal | Not Specified | Not Specified | details | |
| Phosphorylcholine (HMDB0001565) | 2.16 +/- 0.84 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Ribitol (HMDB0000508) | 3.8 +/- 0.68 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Sorbitol (HMDB0000247) | 22.89 +/- 3.34 uM | Abnormal | Not Specified | Not Specified | details | |
| Zinc (HMDB0015532) | 1.83 +/- 1.38 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Thiamine pyrophosphate (HMDB0001372) | 0.0025 +/- 0.0017 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Thiamine monophosphate (HMDB0002666) | 0.0035 +/- 0.0038 uM | Abnormal | Adult (>18 years old) | Both | details | |
| 1,5-Anhydrosorbitol (HMDB0002712) | 41.7 +/-13.7 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Arabitol (HMDB0001851) | 22.4 +/- 4.6 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Galactitol (HMDB0000107) | 1.65 +/- 0.22 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Mannitol (HMDB0000765) | 5.6 +/-1.1 uM | Abnormal | Adult (>18 years old) | Both | details | |
| myo-Inositol (HMDB0000211) | 158.8 +/- 27.2 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Sorbitol (HMDB0000247) | 23.3 +/- 3.3 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Copper (HMDB0000657) | 1.39 +/- 1.02 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Fe2+ (HMDB0000692) | 1.8 +/- 1.8 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Manganese (HMDB0001333) | 0.0146 +/- 0.0146 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Zinc (HMDB0015532) | 1.6 +/- 1.6 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Prolylhydroxyproline (HMDB0006695) | 0.086 +/- 0.016 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Folic acid (HMDB0000121) | 0.008 +/- 0.0011 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Glycylproline (HMDB0000721) | 0.086 +/- 0.016 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Choline (HMDB0000097) | 2.5 +/- 1.0 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| 8-Hydroxyguanosine (HMDB0002044) | 0.00050 +/- 0.00021 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| L-Arginine (HMDB0000517) | 6.0 +/- 1.4 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Tryptophan (HMDB0000929) | 1.3 +/- 0.32 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Tyrosine (HMDB0000158) | 27.18 +/- 4.8 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Dopamine (HMDB0000073) | 0.34 +/- 0.10 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Citrulline (HMDB0000904) | 27.0 +/- 2.6 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Glutamine (HMDB0000641) | 1146.6 +/- 10.6 uM | Abnormal | Adult (>18 years old) | Both | details | |
| 4-Hydroxyproline (HMDB0000725) | 0.28 +/- 0.055 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Asparagine (HMDB0000168) | 1.77 +/- 0.16 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Isoleucine (HMDB0000172) | 2.4 +/- 0.65 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Lysine (HMDB0000182) | 44.6 +/- 10.8 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Cystine (HMDB0000192) | 7.8 +/- 2.5 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Glycine (HMDB0000123) | 0.28 +/- 0.12 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Valine (HMDB0000883) | 4.13 +/- 1.22 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Leucine (HMDB0000687) | 11.5 +/- 1.5 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Histidine (HMDB0000177) | 14.4 +/- 6.32 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Phenylalanine (HMDB0000159) | 6.0 +/- 0.8 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Proline (HMDB0000162) | 0.68 +/- 0.35 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Folic acid (HMDB0000121) | 0.0203 +/- 0.0017 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Homocysteine (HMDB0000742) | 0.216 +/- 0.122 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 1-Methylhistamine (HMDB0000898) | 0.00276 +/- 0.00013 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| S-Adenosylhomocysteine (HMDB0000939) | 0.0269 +/- 0.0062 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Manganese (HMDB0001333) | 0.0328 +/- 0.0164 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Substance P (HMDB0001897) | 0.00002176 +/- 0.000001188 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Substance P (HMDB0001897) | 0.00003111 +/- 0.000002822 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Substance P (HMDB0001897) | 0.00002770 +/- 0.0000020000 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Dynorphin A (HMDB0012935) | 0.00001674 +/- 0.000006976 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| alpha-D-Glucose (HMDB0003345) | 3700.0 (3200.0-4200.0) uM | Abnormal | Adult (>18 years old) | Both | details |
Parkinson's disease (168600 )
| Metabolite | Concentration in CSF | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 3-Methoxytyramine (HMDB0000022) | 0.0005 +/- 0.0003 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Serotonin (HMDB0000259) | 0.0044 (0.00-0.0093) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Taurine (HMDB0000251) | 6.49 (4.60-8.38) uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Cystine (HMDB0000192) | 0.31 +/- 0.06 uM | Abnormal | Adult (>18 years old) | Both | details | |
| 4-Hydroxynonenal (HMDB0004362) | 1.47 (0.71-2.23) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| (R)-N-Methylsalsolinol (HMDB0003626) | 0.008 +/- 0.002 (0.006 - 0.01) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| (R)-Salsolinol (HMDB0005199) | 0.005 +/- 0.001 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 1-Benzyl-1,2,3,4-tetrahydroisoquinoline (HMDB0004087) | 0.0052 (0.0036-0.0068) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| (S)-N-Methylsalsolinol (HMDB0003892) | 0.01 +/- 0.001 (0.0054 - 0.011) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 2(N)-Methyl-norsalsolinol (HMDB0001189) | Not Quantified | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 8-Hydroxyguanosine (HMDB0002044) | 0.0003 +/- 0.00013 (0.00015 - 0.0004) uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| alpha-Tocopherol (HMDB0001893) | 0.11 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Homovanillic acid (HMDB0000118) | 0.16 +/- 0.095 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Malondialdehyde (HMDB0006112) | 5.3 (0.38 - 55.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Biopterin (HMDB0000468) | 0.0085 +/- 0.0003 uM | Abnormal | Not Specified | Not Specified | details | |
| Neopterin (HMDB0000845) | 0.0226 +/- 0.001 uM | Abnormal | Not Specified | Not Specified | details | |
| Homovanillic acid (HMDB0000118) | 0.187 +/- 0.065 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Manganese (HMDB0001333) | 0.0546 +/- 0.0382 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Vanylglycol (HMDB0001490) | 0.0332 +/- 0.00622 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 5-Hydroxytryptophol (HMDB0001855) | 0.0846 +/- 0.0179 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Somatostatin (HMDB0013072) | 0.0000204 +/- 0.0000081 uM | Abnormal | Adult (>18 years old) | Not Specified | details |
Dihydropyrimidinase deficiency (222748 )
| Metabolite | Concentration in CSF | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Dihydrothymine (HMDB0000079) | 0.0 - 24.0 uM | Abnormal | Not Specified | Both | details | |
| Ureidopropionic acid (HMDB0000026) | 0.5 (0.0-1.0) uM | Abnormal | Children (1-13 years old) | Both | details |
Meningitis
| Metabolite | Concentration in CSF | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Adenine (HMDB0000034) | 0.96 (0 - 12.0) uM | Abnormal | Children (1-13 years old) | Not Specified | details | |
| Adenine (HMDB0000034) | 0.5 (0 - 18.0) uM | Abnormal | Children (1-13 years old) | Not Specified | details | |
| Acetoacetic acid (HMDB0000060) | 322.0 (240.0-404.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Alanine (HMDB0000161) | 0.16 (0.13-0.18) uM | Abnormal | Adult (>18 years old) | Both | details | |
| 3-Hydroxybutyric acid (HMDB0000011) | 430 (359-501) uM | Abnormal | Adult (>18 years old) | Both | details | |
| gamma-Aminobutyric acid (HMDB0000112) | 0.00013 +/- 0.00002 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Pyruvic acid (HMDB0000243) | 195.0 (175.0-215.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Urea (HMDB0000294) | 2150.0 (1850.0-2450.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| 24-Hydroxycholesterol (HMDB0001419) | 0.0086 (0.0076-0.0096) uM | Abnormal | Adult (>18 years old) | Both | details | |
| 27-Hydroxycholesterol (HMDB0002103) | 0.006 +/- 0.0006 uM | Abnormal | Adult (>18 years old) | Both | details | |
| 3-Nitrotyrosine (HMDB0001904) | 5.54 (3.99-7.09) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Uric acid (HMDB0000289) | 125.0 (35.5-215.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Ascorbic acid (HMDB0000044) | 11.9 (0.0-24) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Allantoin (HMDB0000462) | 41.3 (21.7-60.9) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Cyclic AMP (HMDB0000058) | 0.034 (0.021-0.046) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Acetyl-N-formyl-5-methoxykynurenamine (HMDB0004259) | 0.28 (0.06-0.50) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Cyclic AMP (HMDB0000058) | 0.033 +/- 0.012 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| gamma-Aminobutyric acid (HMDB0000112) | 0.1 (0.061 - 0.171) uM | Abnormal | Children (1-13 years old) | Both | details | |
| Leukotriene B4 (HMDB0001085) | <0.000297 uM | Abnormal | Not Specified | Not Specified | details | |
| Prostaglandin E2 (HMDB0001220) | 0.00716 (0.000116-0.0142) uM | Abnormal | Not Specified | Not Specified | details | |
| Prostaglandin D2 (HMDB0001403) | 0.000384 (0.000108-0.000880) uM | Abnormal | Not Specified | Not Specified | details | |
| 6-Keto-prostaglandin F1a (HMDB0002886) | 0.00309 (0.000313-0.00548) uM | Abnormal | Children (1-13 years old) | Not Specified | details | |
| Thromboxane B2 (HMDB0003252) | 0.00289 (0.000594-0.00711) uM | Abnormal | Children (1-13 years old) | Not Specified | details | |
| Hyaluronic acid (HMDB0002061) | >10.306 uM | Abnormal | Not Specified | Not Specified | details |