Browsing CSF Metabolite Diseases and Conditions
Clicking on any metabolite link will take you to the Human Metabolome Database.
AIDS
| Metabolite | Concentration in CSF | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 5-Methyltetrahydrofolic acid (HMDB0001396) | 0.026 +/- 0.007 uM | Abnormal | Children (1-13 years old) | Not Specified | details | |
| Mannitol (HMDB0000765) | 48.9 (8.24-144) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Quinolinic acid (HMDB0000232) | 3.78 +/- 0.88 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Leukotriene C4 (HMDB0001198) | 0.000557 uM | Abnormal | Not Specified | Not Specified | details |
Alcoholism
| Metabolite | Concentration in CSF | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Nicotinic acid (HMDB0001488) | 12.2 +/- 0.3 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Nicotinic acid (HMDB0001488) | 6.5 +/- 0.1 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Pantothenic acid (HMDB0000210) | 0.96 +/- 0.47 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Pantothenic acid (HMDB0000210) | 0.80 +/- 0.08 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Riboflavin (HMDB0000244) | 0.18 +/- 0.02 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Riboflavin (HMDB0000244) | 0.14 +/- 0.06 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Thiamine (HMDB0000235) | 0.02 +/- 0.00 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Thiamine (HMDB0000235) | 0.01 +/- 0.00 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| scyllo-Inositol (HMDB0006088) | 72.5 +/- 55.0 uM | Abnormal | Adult (>18 years old) | Both | details |
Alzheimer's disease (104300 )
| Metabolite | Concentration in CSF | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 1-Methylhistidine (HMDB0000001) | 2.6 +/- 1.13 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Folic acid (HMDB0000121) | 0.0056 +/- 0.005 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Methylhistidine (HMDB0000479) | 2.48 +/- 1.58 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Homocysteine (HMDB0000742) | 14.2 +/- 1.7 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Acetylcholine (HMDB0000895) | 0.01 +/- 0.005 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Fumaric acid (HMDB0000134) | 11.0 (2.00-20.0) uM | Abnormal | Elderly (>65 years old) | Both | details | |
| D-Glucose (HMDB0000122) | 3700.0 (3200.0-4200.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Glutamine (HMDB0000641) | 254.0 (152.0-356.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| Glycerophosphocholine (HMDB0000086) | 6.9 +/- 3.2 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Succinic acid (HMDB0000254) | 55.0 (19.0-91.0) uM | Abnormal | Adult (>18 years old) | Both | details | |
| 24-Hydroxycholesterol (HMDB0001419) | 0.0061 (0.0058-0.0064) uM | Abnormal | Elderly (>65 years old) | Both | details | |
| 27-Hydroxycholesterol (HMDB0002103) | 0.0038 +/- 0.0003 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Dopamine (HMDB0000073) | 0.000078 (0.0000065-0.00015) uM | Abnormal | Adult (>18 years old) | Both | details | |
| 3,4-Dihydroxybenzeneacetic acid (HMDB0001336) | 0.0023 (0.00051-0.0042) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 4-Hydroxynonenal (HMDB0004362) | 0.40 +/- 0.030 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 8-Hydroxyguanine (HMDB0002032) | 0.19 (0.15-0.23) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Pentosidine (HMDB0003933) | 12.5 (12.0-13.0) uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 4-Hydroxynonenal (HMDB0004362) | 0.36 +/- 0.03 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Homocysteine (HMDB0000742) | 0.12 +/- 0.062 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Fe2+ (HMDB0000692) | 2.5 +/- 1.8 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Manganese (HMDB0001333) | 14.6 +/- 13.7 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Mannitol (HMDB0000765) | 5.54 +/- 0.82 uM | Abnormal | Not Specified | Not Specified | details | |
| Methylmalonic acid (HMDB0000202) | 0.30 +/- 0.12 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| myo-Inositol (HMDB0000211) | 158.8 +/- 27.2 uM | Abnormal | Not Specified | Not Specified | details | |
| Phosphorylcholine (HMDB0001565) | 2.16 +/- 0.84 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Ribitol (HMDB0000508) | 3.8 +/- 0.68 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Sorbitol (HMDB0000247) | 22.89 +/- 3.34 uM | Abnormal | Not Specified | Not Specified | details | |
| Zinc (HMDB0015532) | 1.83 +/- 1.38 uM | Abnormal | Elderly (>65 years old) | Not Specified | details | |
| Thiamine pyrophosphate (HMDB0001372) | 0.0025 +/- 0.0017 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Thiamine monophosphate (HMDB0002666) | 0.0035 +/- 0.0038 uM | Abnormal | Adult (>18 years old) | Both | details | |
| 1,5-Anhydrosorbitol (HMDB0002712) | 41.7 +/-13.7 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Arabitol (HMDB0001851) | 22.4 +/- 4.6 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Galactitol (HMDB0000107) | 1.65 +/- 0.22 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Mannitol (HMDB0000765) | 5.6 +/-1.1 uM | Abnormal | Adult (>18 years old) | Both | details | |
| myo-Inositol (HMDB0000211) | 158.8 +/- 27.2 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Sorbitol (HMDB0000247) | 23.3 +/- 3.3 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Copper (HMDB0000657) | 1.39 +/- 1.02 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Fe2+ (HMDB0000692) | 1.8 +/- 1.8 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Manganese (HMDB0001333) | 0.0146 +/- 0.0146 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Zinc (HMDB0015532) | 1.6 +/- 1.6 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Prolylhydroxyproline (HMDB0006695) | 0.086 +/- 0.016 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Folic acid (HMDB0000121) | 0.008 +/- 0.0011 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Glycylproline (HMDB0000721) | 0.086 +/- 0.016 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| Choline (HMDB0000097) | 2.5 +/- 1.0 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| 8-Hydroxyguanosine (HMDB0002044) | 0.00050 +/- 0.00021 uM | Abnormal | Elderly (>65 years old) | Both | details | |
| L-Arginine (HMDB0000517) | 6.0 +/- 1.4 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Tryptophan (HMDB0000929) | 1.3 +/- 0.32 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Tyrosine (HMDB0000158) | 27.18 +/- 4.8 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Dopamine (HMDB0000073) | 0.34 +/- 0.10 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Citrulline (HMDB0000904) | 27.0 +/- 2.6 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Glutamine (HMDB0000641) | 1146.6 +/- 10.6 uM | Abnormal | Adult (>18 years old) | Both | details | |
| 4-Hydroxyproline (HMDB0000725) | 0.28 +/- 0.055 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Asparagine (HMDB0000168) | 1.77 +/- 0.16 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Isoleucine (HMDB0000172) | 2.4 +/- 0.65 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Lysine (HMDB0000182) | 44.6 +/- 10.8 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Cystine (HMDB0000192) | 7.8 +/- 2.5 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Glycine (HMDB0000123) | 0.28 +/- 0.12 uM | Abnormal | Adult (>18 years old) | Both | details | |
| L-Valine (HMDB0000883) | 4.13 +/- 1.22 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Leucine (HMDB0000687) | 11.5 +/- 1.5 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Histidine (HMDB0000177) | 14.4 +/- 6.32 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Phenylalanine (HMDB0000159) | 6.0 +/- 0.8 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Proline (HMDB0000162) | 0.68 +/- 0.35 uM | Abnormal | Adult (>18 years old) | Both | details | |
| Folic acid (HMDB0000121) | 0.0203 +/- 0.0017 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Homocysteine (HMDB0000742) | 0.216 +/- 0.122 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| 1-Methylhistamine (HMDB0000898) | 0.00276 +/- 0.00013 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| S-Adenosylhomocysteine (HMDB0000939) | 0.0269 +/- 0.0062 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Manganese (HMDB0001333) | 0.0328 +/- 0.0164 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Substance P (HMDB0001897) | 0.00002176 +/- 0.000001188 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Substance P (HMDB0001897) | 0.00003111 +/- 0.000002822 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Substance P (HMDB0001897) | 0.00002770 +/- 0.0000020000 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Dynorphin A (HMDB0012935) | 0.00001674 +/- 0.000006976 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| alpha-D-Glucose (HMDB0003345) | 3700.0 (3200.0-4200.0) uM | Abnormal | Adult (>18 years old) | Both | details |
Amyotrophic lateral sclerosis (105400 )
| Metabolite | Concentration in CSF | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Prostaglandin E2 (HMDB0001220) | 35.0 +/- 10.0 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Nitrate (HMDB0002878) | 102.0 +/- 33.0 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Quinolinic acid (HMDB0000232) | 0.06 +/- 0.01 uM | Abnormal | Adult (>18 years old) | Female | details | |
| Manganese (HMDB0001333) | 0.0400 +/- 0.0273 uM | Abnormal | Adult (>18 years old) | Not Specified | details | |
| Picolinic acid (HMDB0002243) | 0.36 +/- 0.04 uM | Abnormal | Adult (>18 years old) | Male | details | |
| Picolinic acid (HMDB0002243) | 0.37 +/- 0.06 uM | Abnormal | Adult (>18 years old) | Female | details |